Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575598 | 1.00 | METAP1 (0.49) | METAP1HRH3ABCB1LMNAHTR2A | |
| SCHEMBL28397007 | 0.98 | HTR2A (0.47) | METAP1HRH3ABCB1LMNAHTR2A | |
| SCHEMBL15688648 | 0.81 | SIGMAR1 (0.46) | HRH3LMNAHTR2ATSHR | |
| SCHEMBL295894 | 0.81 | L3MBTL1 (0.49) | LMNAHTR2ATSHR | |
| SCHEMBL8819866 | 0.80 | ABCB1 (0.55) | ABCB1LMNATSHRADRA2AADRA2B | |
| SCHEMBL21995339 | 0.80 | ACHE (0.52) | HRH3LMNAHTR2A | |
| SCHEMBL8820497 | 0.78 | ABCB1 (0.53) | ABCB1LMNAHTR2AADRA2AADRA2B | |
| SCHEMBL2050300 | 0.77 | TSHR (0.39) | METAP1HRH3HTR2ATSHRCHRNA7 | |
| SCHEMBL2052235 | 0.77 | TSHR (0.39) | METAP1HRH3HTR2ATSHRCHRNA7 | |
| SCHEMBL3816899 | 0.76 | HTR2A (0.42) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079737-B1 | SYSTEM AND METHOD FOR SOLUTION PHASE GAP PEPTIDE SYNTHESIS | UNIV TEXAS TECH SYSTEM (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4644406-A1 | RADIOLABELED MEDICINE | National University Corporation Chiba University (JP) | 2025-11-05 | — | — | EP | disclosed |
| US-12344632-B2 | System and method for solution phase gap peptide synthesis | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-07-01 | — | — | US | disclosed |
| US-20240391949-A1 | COMPOSITIONS AND METHODS FOR CHEMICAL SYNTHESIS | SEDERMA (FR) | 2024-11-28 | — | — | US | disclosed |
| WO-2024150477-A1 | METHOD FOR PRODUCING AMINO GROUP-CONTAINING COMPOUND, METHOD FOR SEPARATING AMINO GROUP-CONTAINING COMPOUND, AND APPARATUS FOR PRODUCING AMINO GROUP-CONTAINING COMPOUND | 株式会社トクヤマ | 2024-07-18 | — | — | WO | disclosed |
| EP-3689892-B1 | RADIOACTIVE DRUG | UNIV CHIBA NAT UNIV CORP (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-12030888-B2 | Himastatin derivatives, and processes of preparation thereof, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-09 | — | — | US | disclosed |
| WO-2024143314-A1 | RADIOLABELED MEDICINE | 国立大学法人千葉大学 | 2024-07-04 | — | — | WO | disclosed |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | SEDERMA (FR) | 2024-07-04 | — | — | US | disclosed |
| US-12024537-B2 | Compositions and methods for chemical synthesis | SEDERMA (FR) | 2024-07-02 | — | — | US | disclosed |
| EP-0292729-B1 | PROCESS FOR SOLID PHASE PEPTIDE SYNTHESIS | BACHEM AG (CH) | 1992-04-22 | — | — | EP | disclosed |
| US-5101059-A | Xanthene compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | disclosed |
| EP-0394194-A1 | Protected amino-acids and process for their preparation | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| US-4923901-A | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4914151-A | Resin-linker combination for the solid-phase synthesis of peptides and intermediates | BACHEM FEINCHEMIKALEIN A.G. (CH) | 1990-04-03 | — | — | US | disclosed |
| US-4831084-A | Resin-linker combination for the solid-phase synthesis of peptides and intermediates | BACHEM FEINCHEMIKALIEN A.G. (CH) | 1989-05-16 | — | — | US | disclosed |
| EP-0305929-A2 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0292729-A2 | Process for solid phase peptide synthesis | BACHEM AG (CH) | 1988-11-30 | — | — | EP | disclosed |
| US-4108846-A | FOR PRODUCTION OF POLYPEPTIDES | HOFFMANN-LA ROCHE INC. | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030888-B2 | Himastatin derivatives, and processes of preparation thereof, and uses thereof | PCSK9, HMGCR, PCSK7 | METAP1 288/4885HRH3 1373/4885ABCB1 339/4885 |
| US-12344632-B2 | System and method for solution phase gap peptide synthesis | SBDS, NGLY1, GAP43 | METAP1 320/4885HRH3 3530/4885ABCB1 4056/4885 |
| US-20240391949-A1 | COMPOSITIONS AND METHODS FOR CHEMICAL SYNTHESIS | NGLY1, DNPEP, HM13 | METAP1 278/4885HRH3 3659/4885ABCB1 4802/4885 |
| US-12024537-B2 | Compositions and methods for chemical synthesis | NGLY1, DNPEP, HM13 | METAP1 278/4885HRH3 3659/4885ABCB1 4802/4885 |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | PTMS, DNPEP, ANPEP | METAP1 42/4885HRH3 3498/4885ABCB1 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.