Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782304 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ENCEH1MEN1 | |
| SCHEMBL9332843 | 0.78 | MAPT (0.53) | MAPTALDH1A1KDM4ECASP1CASP7 | |
| SCHEMBL2243907 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2GAA | |
| SCHEMBL7095605 | 0.75 | HSP90AA1 (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL8782843 | 0.74 | GAA (0.41) | MAPTALDH1A1KDM4ECASP1CASP7 | |
| SCHEMBL4078393 | 0.74 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ECASP1CASP7 | |
| SCHEMBL2760999 | 0.73 | HPGD (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2NCEH1 | |
| SCHEMBL20627310 | 0.73 | SMN1; SMN2 (0.45) | MAPTALDH1A1KDM4ESMN1; SMN2CES2 | |
| SCHEMBL4579542 | 0.73 | MAPT (1.00) | MAPTALDH1A1KDM4ECASP1CASP7 | |
| SCHEMBL9750007 | 0.73 | HSP90AA1 (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762211-A1 | Matted radiation-sensitive recording material and process for its production | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0333004-A2 | Light sensitive diazonium compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-20 | — | — | EP | disclosed |