Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757136 | 0.81 | CCR4 (0.38) | NPC1L3MBTL1 | |
| SCHEMBL31258330 | 0.79 | NPC1 (0.40) | CA1CA2CA4CA12CA9 | |
| SCHEMBL8756138 | 0.79 | L3MBTL1 (0.49) | CA1CA2CA4CA12CA9 | |
| SCHEMBL19280572 | 0.79 | NPC1 (0.40) | CA1CA2CA4CA12CA9 | |
| SCHEMBL27277580 | 0.77 | CA2 (0.47) | CA1CA2CA12CA9LOX | |
| SCHEMBL254799 | 0.74 | PARL (0.43) | CA1CA2CA4CA6CA12 | |
| SCHEMBL31167353 | 0.74 | PLCG1 (0.48) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL5026645 | 0.73 | CA1 (0.60) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL12761882 | 0.71 | PLCG1 (0.44) | PLCG1CA1CA2CA4CA12 | |
| SCHEMBL8756139 | 0.70 | CA1 (0.43) | PLCG1CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535613-B1 | Imine compounds and their production | SUMITOMO CHEMICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5410050-A | Reacting imine-substituted benzoxazinone with electrophilic reagent to convert secondary amide to tertiary amide, reacting product with 3,4,5,6-tetrahydrophthalic anhydride to form imide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5247082-A | 6-imino-7-fluoro-1,4-benzoxazin-3-ones, herbicide intermediate | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0535613-A1 | Imine compounds and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-07 | — | — | EP | disclosed |