Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103839 | 0.80 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL27739489 | 0.72 | TP53 (0.46) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL13926744 | 0.71 | HTR4 (0.40) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL8531640 | 0.70 | HTR2A (0.43) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL28754260 | 0.69 | TSHR (0.33) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL8531462 | 0.68 | KDM4E (0.48) | OPRM1OPRK1OPRL1TSHRCYP3A4 | |
| SCHEMBL16103840 | 0.66 | TSHR (0.51) | TSHRNPY5RMEN1KMT2ARPS6KB1 | |
| SCHEMBL31230201 | 0.66 | TSHR (0.51) | TSHRNPY5RMEN1KMT2ARPS6KB1 | |
| SCHEMBL27781705 | 0.66 | HTR6 (0.43) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7296675 | 0.66 | OPRM1 (0.63) | OPRM1OPRD1OPRK1OPRL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623138-B1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNION PHARMA SCIENT APPL (FR) | 1997-05-21 | — | — | EP | disclosed |