Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188508 | 0.88 | MAPT (0.53) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL8759517 | 0.88 | PRKCZ (0.55) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL8759564 | 0.86 | JAK2 (0.51) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL9184045 | 0.85 | HPGD (0.55) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL9431313 | 0.80 | KMT2A (0.55) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL9188762 | 0.77 | RAB9A (0.52) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL8759258 | 0.74 | UBE2N (0.55) | NPC1MAPTKMT2AMEN1JAK2 | |
| SCHEMBL1608957 | 0.71 | CES2 (0.55) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL1608941 | 0.71 | HPGD (0.58) | NPC1MAPTKMT2AMEN1PRKCZ | |
| SCHEMBL9173237 | 0.68 | KMT2A (0.77) | MAPTKMT2AMAPK1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2124859-A | — | — | None | — | — | JP | disclosed |
| EP-0485207-B1 | Stabilized oil-in-water emulsions | RHONE POULENC AGROCHIMIE (FR) | 1997-05-28 | — | — | EP | disclosed |
| US-5475132-A | Fungicide intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1995-12-12 | — | — | US | disclosed |
| US-5342835-A | Antifungal agents based on amides containing a phenyl group | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-30 | — | — | US | disclosed |
| EP-0485207-A1 | Stabilized oil-in-water emulsions | RHONE-POULENC AGROCHIMIE (FR) | 1992-05-13 | — | — | EP | disclosed |
| JP-H02124859-A | ANTIFUNGAL AGENT BASED ON AMIDE CONTAINING PHENYL GROUP | RHONE POULENC AGROCHIM | 1990-05-14 | — | — | JP | disclosed |