Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759517 | 0.88 | PRKCZ (0.55) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL8759782 | 0.88 | NPC1 (0.53) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL8759564 | 0.86 | JAK2 (0.51) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL9184045 | 0.85 | HPGD (0.55) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL9431313 | 0.80 | KMT2A (0.55) | MAPTNPC1KMT2AMEN1MAPK1 | |
| SCHEMBL9188762 | 0.77 | RAB9A (0.52) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL8759258 | 0.74 | UBE2N (0.55) | MAPTNPC1KMT2AMEN1JAK2 | |
| SCHEMBL21189595 | 0.72 | KMT2A (0.64) | MAPTKMT2AGLAHPGDSMN1; SMN2 | |
| SCHEMBL1608957 | 0.71 | CES2 (0.55) | MAPTNPC1KMT2AMEN1PRKCZ | |
| SCHEMBL1608941 | 0.71 | HPGD (0.58) | MAPTNPC1KMT2AMEN1PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475132-A | Fungicide intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1995-12-12 | — | — | US | disclosed |
| US-5342835-A | Antifungal agents based on amides containing a phenyl group | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-30 | — | — | US | disclosed |