Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14986880 | 0.88 | ALOX15 (0.59) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL26215281 | 0.88 | ALOX15 (0.59) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL3257461 | 0.87 | THRA (0.54) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL17206840 | 0.86 | ALOX15 (0.61) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL8761463 | 0.85 | TSHR (0.66) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL24605354 | 0.84 | HIF1A (0.54) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL6336071 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL12370678 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX15ALOX12TSHRHPGD | |
| SCHEMBL10990403 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HIF1AALOX15ALOX12TSHR | |
| SCHEMBL8559584 | 0.79 | THRB (0.49) | ALDH1A1HIF1AALOX15ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497465-B1 | Record material | APPLETON PAPER INC (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0497465-A1 | Record material | APPLETON PAPERS INC. (US) | 1992-08-05 | — | — | EP | disclosed |