Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16741102 | 0.85 | KDM4E (0.47) | SSTR4HTTHSD17B10RBP4NFE2L2 | |
| SCHEMBL28147400 | 0.81 | HSP90AA1 (0.61) | SSTR4HTTLMNAL3MBTL1MEN1 | |
| SCHEMBL16741032 | 0.80 | L3MBTL1 (0.47) | SSTR4HSD17B10RBP4L3MBTL1KDM4E | |
| SCHEMBL2919947 | 0.77 | NAPRT (0.53) | HTTLMNAHDAC6METAP2METAP1 | |
| SCHEMBL5702580 | 0.76 | KDM4E (0.50) | HTTLMNAHDAC6METAP2METAP1 | |
| SCHEMBL18065921 | 0.75 | SSTR4 (0.43) | SSTR4HSD17B10RBP4L3MBTL1KDM4E | |
| SCHEMBL16741099 | 0.75 | SSTR4 (0.42) | SSTR4HTTHSD17B10RBP4NFE2L2 | |
| SCHEMBL377461 | 0.74 | LMNA (0.42) | HTTLMNAHDAC6METAP2METAP1 | |
| SCHEMBL4372362 | 0.74 | TSHR (0.44) | SSTR4HTTHSD17B10RBP4NFE2L2 | |
| SCHEMBL21801971 | 0.74 | SSTR4 (0.38) | SSTR4HTTHSD17B10ELANERBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |