Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761193 | 0.96 | CHRNB2 (0.49) | CHRNB2CHRNA4KDM4EALDH1A1CA12 | |
| SCHEMBL8761203 | 0.89 | CA2 (0.49) | CHRNB2CHRNA4KDM4EALDH1A1CA12 | |
| SCHEMBL9293338 | 0.85 | CA2 (0.49) | CHRNB2CHRNA4KDM4EALDH1A1CA12 | |
| SCHEMBL8761647 | 0.84 | KDM4E (0.55) | CHRNB2CHRNA4KDM4EALDH1A1HRH3 | |
| SCHEMBL8761425 | 0.81 | TRIM24 (0.57) | CHRNB2CHRNA4KDM4EALDH1A1HRH3 | |
| SCHEMBL9293024 | 0.81 | KDM4E (0.52) | CHRNB2CHRNA4KDM4EALDH1A1MAPT | |
| SCHEMBL17743572 | 0.81 | NR5A1 (0.54) | CA12CA2CA1CA9MAPT | |
| SCHEMBL17743570 | 0.81 | NR5A1 (0.54) | CA12CA2CA1CA9MAPT | |
| SCHEMBL8761141 | 0.80 | L3MBTL1 (0.47) | CHRNB2CHRNA4KDM4EALDH1A1HRH3 | |
| SCHEMBL17743542 | 0.77 | CA2 (0.64) | KDM4EALDH1A1CA12CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521787-B1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-04-23 | — | — | EP | claimed |
| EP-0521787-A1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-01-07 | — | — | EP | claimed |
| EP-0521787-B1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-04-23 | — | — | EP | disclosed |
| US-5278154-A | New vanadium complexes | ADIR ET COMPAGNIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5266565-A | Antidiabetic | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0521787-A1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-01-07 | — | — | EP | disclosed |