Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 5/20 | 0.32 |
| ▸ | JAK1 | P23458 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878507 | 0.87 | CCR5 (0.35) | CCR5F10JAK2JAK1POLB | |
| SCHEMBL876130 | 0.86 | POLB (0.35) | CCR5F10JAK2JAK1POLB | |
| SCHEMBL875757 | 0.84 | CCR5 (0.35) | CCR5F10JAK2JAK1POLB | |
| SCHEMBL876267 | 0.84 | F10 (0.36) | CCR5F10JAK2JAK1POLB | |
| SCHEMBL875502 | 0.79 | ALDH1A1 (0.34) | ALDH1A1ALOX15CCR5F10POLB | |
| SCHEMBL786192 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15CCR5F10HRH3 | |
| SCHEMBL785791 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX15CCR5F10JAK2 | |
| SCHEMBL784500 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15CCR5F10JAK2 | |
| SCHEMBL784256 | 0.74 | CCR5 (0.38) | ALDH1A1ALOX15CCR5F10HRH3 | |
| SCHEMBL784953 | 0.73 | POLB (0.39) | ALDH1A1ALOX15CCR5F10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |