Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24847365 | 0.88 | ALDH1A1 (0.36) | CYP1A2CYP3A4CYP2C19CYP2C9KMT2A | |
| SCHEMBL8745424 | 0.74 | MAPK1 (0.33) | CYP1A2CYP3A4CYP2C19CYP2C9GAA | |
| SCHEMBL29207931 | 0.72 | MAPT (0.40) | MAPTCTSVCTSLCTSBCTSS | |
| SCHEMBL8761873 | 0.71 | CYP3A4 (0.46) | CYP1A2CYP3A4CYP2C19CYP2C9KMT2A | |
| SCHEMBL4145479 | 0.68 | HSD17B10 (0.37) | CYP1A2CYP3A4CYP2C19CYP2C9NPSR1 | |
| SCHEMBL13697355 | 0.68 | EPHX1 (0.37) | MAPK1 | |
| SCHEMBL13697353 | 0.67 | ALDH1A1 (0.42) | MAPTCYP1A2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25014158 | 0.66 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL1887090 | 0.65 | MAPT (0.48) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL12963086 | 0.62 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779294-A1 | Halogen-free cyclic phosphoric acid esters and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-18 | — | — | EP | disclosed |