Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830900 | 0.98 | LIPE (0.49) | LIPEHTTL3MBTL1POLBLMNA | |
| SCHEMBL9651145 | 0.79 | LIPE (0.50) | LIPEHTTL3MBTL1POLBLMNA | |
| SCHEMBL15413270 | 0.77 | ALDH1A1 (0.33) | LIPEPOLBALDH1A1CYP3A4 | |
| SCHEMBL26096104 | 0.77 | LIPE (0.48) | LIPEHTTL3MBTL1POLBLMNA | |
| SCHEMBL8682108 | 0.76 | POLB (0.36) | LIPEPOLBALDH1A1CYP3A4GAA | |
| SCHEMBL27519967 | 0.76 | MAPT (0.39) | LIPEL3MBTL1POLBALDH1A1KDM4E | |
| SCHEMBL910451 | 0.75 | LIPE (0.53) | LIPEHTTALDH1A1 | |
| SCHEMBL8682165 | 0.73 | POLB (0.37) | LIPEPOLBNFKB1 | |
| SCHEMBL27699290 | 0.73 | MAPT (0.36) | LIPEMAPT | |
| SCHEMBL8682170 | 0.73 | POLB (0.37) | LIPEPOLBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154181-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2025-05-15 | — | — | US | disclosed |
| US-12173021-B2 | Treprostinil prodrugs | UNITED THERAPEUTICS CORPORATION (US) | 2024-12-24 | — | — | US | disclosed |
| US-20240051979-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2024-02-15 | — | — | US | disclosed |
| US-11634443-B2 | Treprostinil prodrugs | UNITED THERAPEUTICS CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| US-20210054009-A1 | TREPROSTINIL PRODRUGS | UNITED THERAPEUTICS CORPORATION (US) | 2021-02-25 | — | — | US | disclosed |
| EP-0541340-B1 | Biopolymer synthesis apparatus and method | PERKIN ELMER CORP (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5462748-A | Biopolymer synthesis apparatus and method | APPLIED BIOSYSTEMS, INC. (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0541340-A2 | Biopolymer synthesis apparatus and method | THE PERKIN-ELMER CORPORATION (US) | 1993-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154181-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | LIPE 1854/4885HTT 2504/4885L3MBTL1 2526/4885 |
| US-20210054009-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | LIPE 1854/4885HTT 2504/4885L3MBTL1 2526/4885 |
| US-20240051979-A1 | TREPROSTINIL PRODRUGS | TYMP, TK1, DCTPP1 | LIPE 1854/4885HTT 2504/4885L3MBTL1 2526/4885 |
| US-12173021-B2 | Treprostinil prodrugs | TYMP, TK1, DCTPP1 | LIPE 1854/4885HTT 2504/4885L3MBTL1 2526/4885 |
| US-11634443-B2 | Treprostinil prodrugs | TYMP, TK1, DCTPP1 | LIPE 1854/4885HTT 2504/4885L3MBTL1 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.