SCHEMBL8762017

SCHEMBL8762017

CCCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
POLB P06746 1/20 0.57
ALDH1A1 P00352 2/20 0.51
PTGER4 P35408 9/20 0.44
PTGER3 P43115 6/20 0.44
PTGER2 P43116 5/20 0.44
ACE P12821 2/20 0.43
USP2 O75604 1/20 0.42
TP53 P04637 2/20 0.41
GAA P10253 1/20 0.41
P2RX7 Q99572 2/20 0.39
MDM2 Q00987 1/20 0.39
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29833530 1.00 MEN1 (0.57) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL10535003 0.95 MEN1 (0.53) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL10343416 0.95 MEN1 (0.52) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL9152263 0.95 MEN1 (0.52) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL8749215 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL8761610 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL242586 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL3425106 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL8761736 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4
SCHEMBL8754825 0.94 MEN1 (0.51) MEN1KMT2APOLBALDH1A1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
EP-0809103-A2 Stable denaturants for use in electrophoretic techniques and methods of using the same FMC CORPORATION (US) 1997-11-26 EP disclosed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
US-5472946-A Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes DISCOVERY THERAPEUTICS, INC. 1995-12-05 US disclosed
US-5470848-A Penetration enhancers for transdermal delivery of systemic agents DISCOVERY THERAPEUTICS, INC. 1995-11-28 US disclosed
US-5444075-A Penetration enhancers for transdermal delivery of systemic agents MINASKANIAN GEVORK (US) 1995-08-22 US disclosed
US-5411978-A Aging resistance, human skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1995-05-02 US disclosed
US-5338747-A Benzoisothiazolinone-1-dioxide derivatives as elastase inhibitors CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1994-08-16 US disclosed
US-5234959-A Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream WHITBY RESEARCH, INC. (US) 1993-08-10 US disclosed
US-5118676-A Administering carboxylic derivatives as enhancer with systemically active agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
US-5118692-A Penetration enhances for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
EP-0446047-A1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1991-09-11 EP disclosed
US-4996199-A Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1991-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH MEN1 4840/4885KMT2A 2718/4885POLB 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.