Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488143 | 0.85 | MAPT (0.47) | SMN1; SMN2ALDH1A1CYP2C19HPGDMAPT | |
| SCHEMBL8761919 | 0.85 | HPD (0.46) | ALDH1A1CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL8763711 | 0.85 | KMT2A (0.38) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8763732 | 0.80 | SMURF2 (0.37) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8762915 | 0.80 | NR1H4 (0.44) | — | |
| SCHEMBL8762864 | 0.80 | SMURF2 (0.38) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8489206 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CYP2C19HPGDCYP1A2 | |
| SCHEMBL8762913 | 0.79 | SMURF2 (0.38) | NPC1RAB9A | |
| SCHEMBL8634180 | 0.76 | GPBAR1 (0.38) | L3MBTL1POLB | |
| SCHEMBL8762846 | 0.74 | LMNA (0.42) | ALDH1A1CYP2C19MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | claimed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | claimed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | claimed |
| CN-1093537-C | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | PHONE POULENC AGRICULTURE LTD (GB) | 2002-10-30 | — | — | CN | disclosed |
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | disclosed |
| CN-1183411-A | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | RHONE POULENC AGRICULTURE (GB) | 1998-06-03 | — | — | CN | disclosed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | disclosed |