Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342292 | 0.83 | EPHX1 (0.53) | EPHX1CYP4F2CYP4A11APOBEC3GL3MBTL1 | |
| SCHEMBL1395495 | 0.82 | EPHX1 (0.51) | EPHX1CYP4F2CYP4A11APOBEC3GL3MBTL1 | |
| SCHEMBL4787649 | 0.80 | EPHX1 (0.50) | EPHX1CYP4F2CYP4A11APOBEC3GL3MBTL1 | |
| SCHEMBL3628841 | 0.80 | PTGS2 (0.53) | EPHX1CYP4F2CYP4A11TSHRHPGD | |
| SCHEMBL11295860 | 0.77 | EPHX1 (0.48) | EPHX1CYP4F2CYP4A11L3MBTL1TSHR | |
| SCHEMBL16244704 | 0.77 | EPHX1 (0.48) | EPHX1L3MBTL1TSHRHPGDLMNA | |
| SCHEMBL10670224 | 0.77 | EPHX1 (0.48) | EPHX1CYP4F2CYP4A11L3MBTL1THRA | |
| SCHEMBL6668242 | 0.77 | KMT2A (0.59) | EPHX1TSHRLMNAGAAMEN1 | |
| SCHEMBL6219545 | 0.76 | THRB (0.61) | EPHX1CYP4F2CYP4A11L3MBTL1THRA | |
| SCHEMBL2198922 | 0.76 | TSHR (0.61) | EPHX1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599531-B1 | Process for production of 2-acetylbenzo b thiophene | IHARA CHEMICAL IND CO (JP) | 1997-07-09 | — | — | EP | disclosed |