Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395495 | 0.85 | EPHX1 (0.51) | EPHX1CYP4F2CYP4A11HPGDAPOBEC3G | |
| SCHEMBL4787649 | 0.83 | EPHX1 (0.50) | EPHX1CYP4F2CYP4A11HPGDKDM4E | |
| SCHEMBL3628841 | 0.83 | PTGS2 (0.53) | EPHX1CYP4F2CYP4A11HPGDKDM4E | |
| SCHEMBL8762969 | 0.83 | EPHX1 (0.50) | EPHX1CYP4F2CYP4A11HPGDKDM4E | |
| SCHEMBL47950 | 0.83 | L3MBTL1 (0.50) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL29587376 | 0.83 | L3MBTL1 (0.50) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL611227 | 0.81 | CXCL8 (0.40) | EPHX1HPGDKDM4EHSD17B10MTNR1A | |
| SCHEMBL7878460 | 0.81 | HPGD (0.39) | EPHX1HPGDKDM4EHSD17B10MTNR1A | |
| SCHEMBL609102 | 0.81 | CXCL8 (0.40) | EPHX1HPGDKDM4EHSD17B10MTNR1A | |
| SCHEMBL10670224 | 0.80 | EPHX1 (0.48) | EPHX1CYP4F2CYP4A11HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051044-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | UNIVERSITY OF MEDICINE AND DENTISTRY (US) | 2010-05-06 | — | — | WO | disclosed |