Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986152 | 0.88 | HSD17B10 (0.67) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL68677 | 0.86 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL30850062 | 0.86 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL11589528 | 0.86 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL8467353 | 0.85 | PTGS2 (0.54) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| Benzene SCHEMBL28173619 | 0.84 | PTGS2 (0.58) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL10924111 | 0.84 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL3342292 | 0.83 | EPHX1 (0.53) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL18196768 | 0.83 | MAPK1 (0.57) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL4353285 | 0.83 | EPHX1 (0.47) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| WO-2017023774-A9 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-23 | — | — | WO | disclosed |
| WO-2014144073-A2 | AUGMENTING MOIETIES FOR ANTI-INFLAMMATORY COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-2393775-B1 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2014-06-25 | — | — | EP | disclosed |
| US-8575366-B2 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | BASF SE (DE) | 2013-11-05 | — | — | US | disclosed |
| CN-102471234-A | Preparation method of Fe (III) chelate of N, N '-bis (2-hydroxybenzyl) ethylenediamine-N, N' -diacetic acid and derivative thereof | PRZED PROD CONSULTINGOWE ADOB SP Z O O SP K | 2012-05-23 | — | — | CN | disclosed |
| EP-2393775-A2 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20110295022-A1 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | BASE SE (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010089267-A2 | METHOD FOR PRODUCING 2-HALOGENOMETHYLPHENYL ACETIC ACID DERIVATIVES | BASF SE (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-20090068273-A1 | Inhalation devices for delivering phenethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2009-03-12 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| EP-0947512-A1 | Method for manufacturing 3-isochromanone | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0934262-A1 | BETA-THIOPROPIONYL-AMINO ACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017639-A1 | BETA-THIOPROPIONYL-AMINO ACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1998-04-30 | — | — | WO | disclosed |
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | disclosed |
| EP-0377308-B1 | Phenolic resins | BORDEN UK LTD (GB) | 1993-11-03 | — | — | EP | disclosed |
| US-5051454-A | An esterified phenolic compound, an unesterified phenolic resole and a base and curing | BORDEN, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0377308-A1 | Phenolic resins | BORDEN (UK) LIMITED (GB) | 1990-07-11 | — | — | EP | disclosed |
| WO-1990006904-A2 | PHENOLIC RESINS | BORDEN (UK) LIMITED (GB) | 1990-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295022-A1 | Method for producing 2-halogenomethylphenyl acetic acid derivatives | HACL2, AKR7A2, ALAD | PTGS2 1962/4885KDM4E 2612/4885HSD17B10 183/4885 |
| US-20090068273-A1 | Inhalation devices for delivering phenethanolamine derivatives for the treatment of respiratory diseases | PNMT, CHRM3, HRH4 | PTGS2 1135/4885KDM4E 218/4885HSD17B10 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.