Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | GRB2 | P62993 | 1/20 | 0.30 |
| ▸ | BHMT | Q93088 | 5/20 | 0.30 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL8763013 | 0.83 | SMN1; SMN2 (0.38) | — | |
| Triaziquone SCHEMBL1462397 | 0.80 | DNMT1 (0.38) | — | |
| Triaziquone SCHEMBL15269829 | 0.79 | DNMT1 (0.37) | — | |
| Triaziquone SCHEMBL8330857 | 0.78 | GRM8 (0.47) | DPP4DPP7DPP8DPP9BHMT | |
| Methionine SCHEMBL8763034 | 0.76 | BHMT (0.47) | BHMTBHMT2NOS3NOS1NOS2 | |
| Racemethionine SCHEMBL8589228 | 0.76 | BHMT (0.47) | BHMTBHMT2NOS3NOS1NOS2 | |
| Methionine SCHEMBL8589231 | 0.76 | BHMT (0.47) | BHMTBHMT2NOS3NOS1NOS2 | |
| Triaziquone SCHEMBL3641977 | 0.76 | DNMT1 (0.31) | — | |
| Triaziquone SCHEMBL9016339 | 0.75 | DNMT1 (0.36) | DPP4DPP7 | |
| Triaziquone SCHEMBL11583629 | 0.72 | DNMT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783517-A2 | THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-07-16 | — | — | EP | disclosed |