Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29842432 | 0.73 | PKM (0.35) | HTT | |
| SCHEMBL16892930 | 0.72 | LOXL2 (0.47) | ALDH1A1RAB9ASMN1; SMN2NPC1LOXL2 | |
| SCHEMBL4406979 | 0.71 | ALDH1A1 (0.38) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL13811853 | 0.70 | MAOA (0.42) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL12733180 | 0.69 | ALDH1A1 (0.59) | TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13821633 | 0.68 | ALDH1A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6501640 | 0.66 | ACACB (0.49) | TSHRALDH1A1RAB9AHTT | |
| SCHEMBL424305 | 0.65 | KDM4E (0.65) | TSHRALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14889554 | 0.65 | LOXL2 (0.47) | TSHRALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28773068 | 0.65 | BLM (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636141-B1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LTD (GB) | 1997-06-25 | — | — | EP | disclosed |