Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADH1B | P00325 | 2/20 | 0.40 |
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | ADH7 | P40394 | 2/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763412 | 0.93 | LMNA (0.50) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL2595668 | 0.83 | TAAR1 (0.55) | LMNATAAR1CA12CA1CA2 | |
| SCHEMBL2701814 | 0.83 | TMEM97 (0.55) | LMNATAAR1SIGMAR1TMEM97SMN1; SMN2 | |
| SCHEMBL350049 | 0.83 | TAAR1 (0.55) | LMNATAAR1CYP3A4CA12CA1 | |
| SCHEMBL2807183 | 0.83 | ALDH1A1 (0.50) | LMNATAAR1SMN1; SMN2CA12CA1 | |
| SCHEMBL23266841 | 0.83 | GFER (0.52) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL16404456 | 0.83 | L3MBTL1 (0.50) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL10433880 | 0.83 | ADH1B (0.50) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL4364954 | 0.83 | LMNA (0.44) | LMNAADH1BADH1AADH7ADH1C | |
| SCHEMBL2471353 | 0.83 | LMNA (0.65) | LMNATAAR1SMN1; SMN2CYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349195-B1 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5336745-A | Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators | EXXON CHEMICAL PATENTS INC. (US) | 1994-08-09 | — | — | US | disclosed |
| US-5032653-A | Catalysts | EXXON CHEMICAL PATENTS, INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0349195-A2 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-03 | — | — | EP | disclosed |