SCHEMBL8763443

SCHEMBL8763443

c1ccc2c(c1)ccc1n[nH]cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP2A6 P11509 4/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP3A4 P08684 1/20 0.50
HPRT1 P00492 1/20 0.48
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
TYMS P04818 2/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A2 P05177 3/20 0.40
PAX8 Q06710 1/20 0.40
KDM4E B2RXH2 2/20 0.39
GPR3 P46089 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10999649 0.88 TYMS (0.46) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL11063116 0.79 ALDH1A1 (0.57) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL2048246 0.75 PDPK1 (0.47) CYP3A4TYMSNPC1LMNAMAPT
SCHEMBL5201632 0.74 ALDH1A1 (0.46) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL452802 0.74 MAPK10 (0.45) KDM4EMAOA
SCHEMBL19469855 0.74 IMPDH2 (0.42) ALDH1A1CYP3A4LMNACYP1A2KDM4E
Phenanthrene SCHEMBL28225171 0.73 ALDH1A1 (0.75) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL9837615 0.72 MAPT (0.67) ALDH1A1TSHRCYP3A4HIF1ACYP1B1
Phenanthrene SCHEMBL30932938 0.72 CYP2A6 (1.00) ALDH1A1CYP2A6HSD17B10TSHRTDP1
Phenanthrene SCHEMBL29477074 0.72 CYP2A6 (1.00) ALDH1A1CYP2A6HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805388-B Organic compound containing naphtho-diazole structure and preparation method and application thereof 烟台九目化学股份有限公司 2023-04-07 CN claimed
EP-0218385-B2 Thermally developable light-sensitive material KONISHIROKU PHOTO IND (JP) 1997-05-14 EP claimed
EP-0112162-B2 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-08-19 EP claimed
US-4837141-A COMPOUND COMPRISING INHIBITOR RESIDUE LINKED TO AN IMMOBILIZING GROUP TO REDUCT SILVER DIFFUSION; ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-06 US claimed
EP-0112162-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1989-04-12 EP claimed
US-4701405-A OXAZOLINE AND IMIDAZOLINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-10-20 US claimed
EP-0218385-A2 Thermally developable light-sensitive material KONICA CORPORATION (JP) 1987-04-15 EP claimed
EP-0112162-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1984-06-27 EP claimed
CN-115003663-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-04-30 CN disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 CN disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed
CN-113347882-B Herbicidal composition 拜耳公司 2023-12-19 CN disclosed
CN-116828985-A Storage-stable aqueous suspension concentrates 拜耳公司 2023-09-29 CN disclosed
CN-110234627-B Pyridone compound and agricultural/horticultural bactericide containing pyridone compound as active ingredient 三井化学植保株式会社 2023-09-01 CN disclosed
EP-0112162-B2 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-08-19 EP disclosed
US-4837141-A COMPOUND COMPRISING INHIBITOR RESIDUE LINKED TO AN IMMOBILIZING GROUP TO REDUCT SILVER DIFFUSION; ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-06 US disclosed
EP-0112162-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1989-04-12 EP disclosed
US-4701405-A OXAZOLINE AND IMIDAZOLINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-10-20 US disclosed
EP-0218385-A2 Thermally developable light-sensitive material KONICA CORPORATION (JP) 1987-04-15 EP disclosed
EP-0112162-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1984-06-27 EP disclosed