SCHEMBL8763541

SCHEMBL8763541

CSc1cc(Cc2cc(SC)c(N)c(SC)c2)cc(SC)c1N

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765289 0.86 ALDH1A1 (0.43) ALDH1A1CYP3A4TSHRTDP1GAA
SCHEMBL8764624 0.86 ALDH1A1 (0.43) ALDH1A1CYP3A4TSHRTDP1GAA
SCHEMBL9578966 0.83 LOXL2 (0.33)
SCHEMBL8763661 0.79 HTR2A (0.39) ALDH1A1TDP1
SCHEMBL8446954 0.76 ALDH1A1 (0.38) ALDH1A1CYP3A4TSHRGAA
SCHEMBL10569631 0.76 ALDH1A1 (0.45) ALDH1A1CYP3A4TSHRTDP1GAA
SCHEMBL9578934 0.76 ALDH1A1 (0.41) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL10886034 0.75 SHBG (0.43)
SCHEMBL10943765 0.75 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRTDP1GAA
SCHEMBL10573288 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US claimed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US claimed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP claimed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO claimed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US claimed
EP-0635034-B1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEM CO INC (US) 1997-07-30 EP claimed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO claimed
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US disclosed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US disclosed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP disclosed
US-8821663-B2 Ballistic resilient run-flat tire, kit and method thereof ARNCO (US) 2014-09-02 US disclosed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO disclosed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US disclosed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO disclosed
US-5223599-A Polyetherurethanes and alkylthioaromatic amine curing agents, which are non-carcinogenic UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-29 US disclosed
EP-0193872-B1 DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS ETHYL CORPORATION (US) 1993-03-31 EP disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed
EP-0193872-A2 Di(alkylthio) diamine chain extenders for polyurethane elastomers ETHYL CORPORATION (US) 1986-09-10 EP disclosed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US disclosed