Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765289 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EMAPTRAB9A | |
| SCHEMBL10943765 | 0.92 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EMAPTRAB9A | |
| SCHEMBL9799468 | 0.88 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EMAPTRAB9A | |
| SCHEMBL8763541 | 0.86 | ALDH1A1 (0.31) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL11896057 | 0.79 | SLC6A2 (0.40) | ALDH1A1GAAMAPTRAB9AMEN1 | |
| SCHEMBL10876001 | 0.79 | LOXL2 (0.39) | ALDH1A1GAARAB9AMEN1KMT2A | |
| SCHEMBL11896102 | 0.76 | SKP2 (0.46) | ALDH1A1GAAMAPTRAB9AMEN1 | |
| SCHEMBL20091810 | 0.74 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EMAPTRAB9A | |
| SCHEMBL11529316 | 0.72 | CYP3A4 (0.48) | ALDH1A1GAAKDM4EMAPTRAB9A | |
| SCHEMBL9578966 | 0.71 | LOXL2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635034-B1 | POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM | UNIROYAL CHEM CO INC (US) | 1997-07-30 | — | — | EP | claimed |
| EP-0193872-B1 | DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS | ETHYL CORPORATION (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0289870-A2 | Epoxy resin compositions | ETHYL CORPORATION (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4757119-A | Diamine curing agent | ETHYL CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0193872-A2 | Di(alkylthio) diamine chain extenders for polyurethane elastomers | ETHYL CORPORATION (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4595742-A | Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine | ETHYL CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |