Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966598 | 0.85 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL966645 | 0.84 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL966413 | 0.82 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL965813 | 0.77 | CCR5 (0.39) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL13911238 | 0.73 | ADH1A (0.43) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL968899 | 0.71 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL13900746 | 0.71 | EPHX1 (0.40) | L3MBTL1NPC1MEN1KMT2ALMNA | |
| SCHEMBL9547591 | 0.71 | NAAA (0.47) | ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL27689547 | 0.70 | SLC6A4 (0.39) | KMT2AEPHX1CCR5 | |
| SCHEMBL6467642 | 0.70 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781272-A1 | NOVEL SYNTHESIS OF PENTA-SUBSTITUTED GUANIDINES | MONSANTO COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008469-A1 | NOVEL SYNTHESIS OF PENTA-SUBSTITUTED GUANIDINES | MONSANTO COMPANY (US) | 1996-03-21 | — | — | WO | disclosed |