SCHEMBL876382

SCHEMBL876382

C=CCN(C)c1ccc(/N=N/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.57
MAPT P10636 9/20 0.49
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
MAPK1 P28482 4/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
TNNI3 P19429 1/20 0.49
TNNT2 P45379 1/20 0.49
TNNC1 P63316 1/20 0.49
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
ALDH1A1 P00352 8/20 0.44
TDP1 Q9NUW8 4/20 0.44
GAA P10253 2/20 0.43
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL876383 1.00 MMP14 (0.57) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL887932 0.94 MMP14 (0.52) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL876446 0.91 MAPT (0.57) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL8917217 0.87 MMP14 (0.46) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL8917221 0.87 MMP14 (0.46) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL8612280 0.86 MAPT (0.57) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL3263007 0.85 MMP14 (0.47) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL3263010 0.85 MMP14 (0.47) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL17787279 0.82 MMP14 (0.63) MMP14MAPTMEN1KMT2AMAPK1
SCHEMBL14063276 0.82 MMP14 (0.63) MMP14MAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2619250-A1 DIELECTRIC POLYMERS WITH ELEVATED PERMITTIVITY, PROCESS FOR PREPARATION THEREOF AND END USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-07-31 EP disclosed
WO-2012038093-A1 DIELECTRIC POLYMERS WITH ELEVATED PERMITTIVITY, PROCESS FOR PREPARATION THEREOF AND END USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2012-03-29 WO disclosed