Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917221 | 1.00 | MMP14 (0.46) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8612280 | 0.88 | MAPT (0.57) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL876382 | 0.87 | MMP14 (0.57) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL876383 | 0.87 | MMP14 (0.57) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL887932 | 0.81 | MMP14 (0.52) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8641019 | 0.81 | MMP14 (0.44) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL876446 | 0.78 | MAPT (0.57) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8611566 | 0.78 | MAPT (0.44) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3263007 | 0.76 | MMP14 (0.47) | MMP14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3263010 | 0.76 | MMP14 (0.47) | MMP14MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663308-A | DYES CONTAINING ELECTRON DONOR/ACEPTOR GROUPS LINKED BY DELOCALIZED PI ELECTRON SYSTEM AND TWO OR MORE PENDANT GROUPS | HERCULES INCORPORATED (US) | 1997-09-02 | — | — | US | disclosed |
| US-5298588-A | Organosilicon polymers, and dyes, exhibiting nonlinear optical response | HERCULES INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-5254655-A | Made by hydrosilation of cyclic polysiloxanes and carbon-carbon bond-containing dye | HERCULES INCORPORATED (US) | 1993-10-19 | — | — | US | disclosed |