Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876383 | 0.94 | MMP14 (0.57) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL876382 | 0.94 | MMP14 (0.57) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL876446 | 0.85 | MAPT (0.57) | MMP14MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL8917217 | 0.81 | MMP14 (0.46) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8917221 | 0.81 | MMP14 (0.46) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8612280 | 0.80 | MAPT (0.57) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3263007 | 0.80 | MMP14 (0.47) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3263010 | 0.80 | MMP14 (0.47) | MMP14MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8610429 | 0.78 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8610431 | 0.78 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | disclosed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20080248474-A1 | AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248474-A1 | AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC (US) | 2008-10-09 | — | — | US | disclosed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7319022-B1 | Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe | EPOCH BIOSCIENCES, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319022-B1 | Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe | EPOCH BIOSCIENCES, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | MMP14 4362/4885MAPT 4706/4885NPC1 2322/4885 |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | RNGTT, DCLRE1B, CNBP | MMP14 552/4885MAPT 4694/4885NPC1 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.