SCHEMBL876446

SCHEMBL876446

C=CCN(C)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
CRHBP P24387 2/20 0.51
CRHR2 Q13324 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP1A2 P05177 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
PHLPP2 Q6ZVD8 1/20 0.47
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
MMP14 P50281 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
TLR9 Q9NR96 1/20 0.44
LSS P48449 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL876383 0.91 MMP14 (0.57) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL876382 0.91 MMP14 (0.57) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL887932 0.85 MMP14 (0.52) MAPTCRHBPCRHR2TDP1MAPK1
SCHEMBL8674454 0.84 ALDH1A1 (0.49) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL129460 0.82 ALDH1A1 (0.48) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL11501045 0.81 PYCR1 (0.41) CYP3A4TDP1TSHRMAPK1ALDH1A1
SCHEMBL9748257 0.80 MAPT (0.62) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL18660127 0.80 MAPT (0.77) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL9754758 0.79 ALDH1A1 (0.46) MAPTCRHBPCRHR2L3MBTL1CYP3A4
SCHEMBL8917221 0.78 MMP14 (0.46) MAPTCRHBPCRHR2L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101928613-A The compoistion and method of use that contains ignition dope AFTON CHEMICAL CORP 2010-12-29 CN claimed
US-9018320-B2 Dielectric polymers with elevated permittivity, process for preparation thereof and end uses thereof Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2015-04-28 US disclosed
US-20130253146-A1 DIELECTRIC POLYMERS WITH ELEVATED PERMITTIVITY, PROCESS FOR PREPARATION THEREOF AND END USES THEREOF FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2013-09-26 US disclosed
EP-2619250-A1 DIELECTRIC POLYMERS WITH ELEVATED PERMITTIVITY, PROCESS FOR PREPARATION THEREOF AND END USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-07-31 EP disclosed
WO-2012038093-A1 DIELECTRIC POLYMERS WITH ELEVATED PERMITTIVITY, PROCESS FOR PREPARATION THEREOF AND END USES THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2012-03-29 WO disclosed
CN-101928613-A The compoistion and method of use that contains ignition dope AFTON CHEMICAL CORP 2010-12-29 CN disclosed
EP-0554904-B1 Organosilicon polymers, and dyes, exhibiting nonlinear optical response ALLIANT TECHSYSTEMS INC (US) 1998-06-10 EP disclosed
US-5714304-A AN ORGANOSILICON CROSSLINKED POLYMER IS THE REACTION PRODUCT OF ATLEAST ONE CYCLIC POLYSILOXANE HAVING ATLEAST TWO HYDROSILATION REACTIVE GROUPS, AN ORGANIC DYE WITH ELECTRON ACCEPTOR AND DONOR GROUPS WITH DOUBLE BOND, AND A POLYENE HERCULES INCORPORATED (US) 1998-02-03 US disclosed
US-5663308-A DYES CONTAINING ELECTRON DONOR/ACEPTOR GROUPS LINKED BY DELOCALIZED PI ELECTRON SYSTEM AND TWO OR MORE PENDANT GROUPS HERCULES INCORPORATED (US) 1997-09-02 US disclosed
US-5605726-A FILMS, SEMICONDUCTORS HERECULES INCORPORATED (US) 1997-02-25 US disclosed
US-5298588-A Organosilicon polymers, and dyes, exhibiting nonlinear optical response HERCULES INCORPORATED (US) 1994-03-29 US disclosed
US-5254655-A Made by hydrosilation of cyclic polysiloxanes and carbon-carbon bond-containing dye HERCULES INCORPORATED (US) 1993-10-19 US disclosed
EP-0554904-A2 Organosilicon polymers, and dyes, exhibiting nonlinear optical response HERCULES INCORPORATED (US) 1993-08-11 EP disclosed