⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473248 | 0.92 | L3MBTL1 (0.32) | — | |
| SCHEMBL95795 | 0.82 | — | — | |
| SCHEMBL27621465 | 0.80 | MAPT (0.34) | — | |
| SCHEMBL25181908 | 0.78 | — | — | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | — | |
| SCHEMBL596640 | 0.77 | L3MBTL1 (0.37) | — | |
| SCHEMBL446382 | 0.77 | CSNK2A1 (0.40) | — | |
| SCHEMBL4881875 | 0.77 | L3MBTL1 (0.40) | — | |
| SCHEMBL6541679 | 0.76 | CA1 (0.38) | — | |
| SCHEMBL96297 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| CN-118206551-A | Quinoline compounds, their preparation and their use as antimalarial agents | 美国卫生和人力服务部 | 2024-06-18 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| EP-3893645-B1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2024-04-17 | — | — | EP | claimed |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-31 | — | — | US | claimed |
| EP-3601216-B1 | SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-25 | — | — | EP | claimed |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-05 | — | — | US | claimed |
| US-11753408-B2 | Compounds and method for blocking transmission of malarial parasite | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-12 | — | — | US | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-1260795-A | quaternary ammonium compounds as tachykinin antagonists | PFIZER LTD (US) | 2000-07-19 | — | — | CN | claimed |
| CN-1247537-A | Sulfonamide compounds having 5-HT receptor activity | KNOLL AG (DE) | 2000-03-15 | — | — | CN | claimed |
| CN-1207094-A | Phenyl thiazole derivatives with anti herpes virus properties | BOEHRINGER INGELHEIM PHARMA (US) | 1999-02-03 | — | — | CN | claimed |
| CN-1020106-C | Process for pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1993-03-17 | — | — | CN | claimed |
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| CN-1030584-A | Novel thiophene derivant and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-01-25 | — | — | CN | claimed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | claimed |
| CN-87105758-A | Pyrimidine derivatives, their production and use | — | 1988-03-02 | — | — | CN | claimed |
| US-4179515-A | HYPOLIPEMIC, HYPOCHOLESTEROLEMIC, CHOLAGOGIC | ORCHIMED S. A. (CH) | 1979-12-18 | — | — | US | claimed |