Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764380 | 0.89 | TSHR (0.41) | HSD11B1MEN1KMT2AS1PR5 | |
| SCHEMBL8764701 | 0.89 | HSD11B1 (0.37) | HSD11B1MEN1KMT2AOPRM1GRM2 | |
| SCHEMBL8762671 | 0.87 | MAOA (0.36) | LMNA | |
| SCHEMBL8763747 | 0.86 | PTGS1 (0.39) | MEN1KMT2A | |
| SCHEMBL8762760 | 0.85 | ALDH1A1 (0.42) | GRM2GRM3 | |
| SCHEMBL8763796 | 0.83 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL8763834 | 0.81 | — | — | |
| SCHEMBL8762717 | 0.80 | GRM2 (0.44) | KMT2AGRM2GRM3 | |
| SCHEMBL8763892 | 0.80 | HSD11B1 (0.39) | L3MBTL1HSD11B1GRM2GRM3 | |
| SCHEMBL8892101 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |