Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764367 | 0.89 | L3MBTL1 (0.41) | HSD11B1MEN1KMT2AOPRM1GRM2 | |
| SCHEMBL8764776 | 0.88 | DDB1 (0.38) | HSD11B1 | |
| SCHEMBL8763834 | 0.88 | — | — | |
| SCHEMBL8764380 | 0.88 | TSHR (0.41) | HSD11B1MEN1KMT2A | |
| SCHEMBL8764215 | 0.86 | CYP26A1 (0.38) | MEN1KMT2AHTT | |
| SCHEMBL8763790 | 0.85 | HSD11B1 (0.40) | HSD11B1MEN1KMT2A | |
| SCHEMBL8763747 | 0.85 | PTGS1 (0.39) | MEN1KMT2AHTT | |
| SCHEMBL8763796 | 0.85 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL8762997 | 0.84 | RIPK1 (0.38) | HSD11B1HTT | |
| SCHEMBL8764456 | 0.84 | TRPA1 (0.36) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |