SCHEMBL8764403

SCHEMBL8764403

CCCCC(CC)Cc1cc(Br)c(O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
BCL2L1 Q07817 1/20 0.34
TSHR P16473 3/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CA2 P00918 3/20 0.33
TYR P14679 1/20 0.33
MAPK1 P28482 1/20 0.33
GLA P06280 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1040922 0.83 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL15738357 0.83 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL8763520 0.81 ALDH1A1 (0.39) ALDH1A1LMNATDP1BCL2L1TSHR
SCHEMBL11039409 0.76 TYR (0.57) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL11328765 0.76 TYR (0.45) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL15738911 0.76 ALOX15 (0.38) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL27543288 0.75 TYR (0.40) ALDH1A1LMNATDP1BCL2L1TSHR
SCHEMBL2483269 0.75 BCL2L1 (0.38) ALDH1A1LMNATDP1BCL2L1TSHR
SCHEMBL69600 0.74 TYR (0.53) ALDH1A1TDP1TSHRCYP3A4ALOX15
SCHEMBL11691535 0.74 ALDH1A1 (0.41) ALDH1A1LMNATDP1BCL2L1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed