Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764066 | 0.91 | GRM2 (0.49) | GRM2GRM3ALDH1A1CA12CA1 | |
| SCHEMBL8763799 | 0.91 | GRM2 (0.49) | GRM2GRM3ALDH1A1CA12CA1 | |
| SCHEMBL8892415 | 0.89 | PPARG (0.34) | GRM2GRM3ALDH1A1KDM4ESLC6A3 | |
| SCHEMBL8891460 | 0.88 | MAPT (0.34) | GRM2GRM3ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL8891587 | 0.87 | MEN1 (0.36) | GRM2GRM3ALDH1A1TSHRMAPT | |
| SCHEMBL8474292 | 0.85 | MAPK8 (0.33) | GRM2GRM3ALDH1A1CA12CA1 | |
| SCHEMBL8892810 | 0.76 | GRM2 (0.33) | GRM2GRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8892402 | 0.76 | GRM2 (0.33) | GRM2GRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8762788 | 0.69 | GRM2 (0.33) | GRM2GRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8902155 | 0.68 | GRM2 (0.34) | GRM2GRM3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |