Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892415 | 0.90 | PPARG (0.34) | MEN1KMT2AALDH1A1MAPTGRM2 | |
| SCHEMBL8764066 | 0.89 | GRM2 (0.49) | MEN1KMT2AALDH1A1TSHRGRM2 | |
| SCHEMBL8763799 | 0.89 | GRM2 (0.49) | MEN1KMT2AALDH1A1TSHRGRM2 | |
| SCHEMBL8764436 | 0.87 | GRM2 (0.38) | ALDH1A1MAPTTSHRGRM2GRM3 | |
| SCHEMBL8474292 | 0.85 | MAPK8 (0.33) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8892582 | 0.64 | DPP4 (0.32) | MEN1KMT2AALDH1A1HSD11B1LMNA | |
| SCHEMBL20730984 | 0.63 | GRM2 (0.42) | MEN1KMT2AALDH1A1MAPTGRM2 | |
| SCHEMBL20731925 | 0.63 | GRM2 (0.42) | MEN1KMT2AALDH1A1MAPTGRM2 | |
| SCHEMBL20731962 | 0.63 | GRM2 (0.42) | MEN1KMT2AALDH1A1MAPTGRM2 | |
| SCHEMBL19508460 | 0.63 | GRM2 (0.42) | MEN1KMT2AALDH1A1MAPTGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |