SCHEMBL8764559

SCHEMBL8764559

CCC(Br)C=C(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
LCK P06239 1/20 0.30
PPARD Q03181 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30
APEX1 P27695 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360502 1.00 ALDH1A1 (0.32) ALDH1A1PTGS1AKR1C3LCKPPARD
SCHEMBL9767228 0.78 PTGS1 (0.32) ALDH1A1PTGS1AKR1C3APEX1
SCHEMBL1000711 0.78 PTGS1 (0.32) ALDH1A1PTGS1AKR1C3APEX1
SCHEMBL9231077 0.78 PTGS1 (0.32) ALDH1A1PTGS1AKR1C3APEX1
SCHEMBL3847914 0.77 APEX1 (0.33) ALDH1A1APEX1
SCHEMBL18173540 0.77 LCK (0.55) LCKPPARDZDHHC20ZDHHC2
SCHEMBL711050 0.76 GAPDH (0.38) PTGS1AKR1C3APEX1
SCHEMBL74357 0.76 GRIK1 (0.31) PTGS1AKR1C3APEX1
SCHEMBL74358 0.76 GRIK1 (0.31) PTGS1AKR1C3APEX1
SCHEMBL16667 0.76 GAPDH (0.38) PTGS1AKR1C3APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0567379-B1 Photochemically crosslinked material for non-linear optical application THOMSON CSF (FR) 1997-07-23 EP claimed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed