SCHEMBL8764599

SCHEMBL8764599

CCP(=O)(COS(=O)(=O)c1c(C)cccc1Cl)OOC(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.33
RORC P51449 1/20 0.31
CCL5 P13501 1/20 0.31
CCR5 P51681 1/20 0.31
SLC40A1 Q9NP59 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8762813 0.93 KMT2A (0.31)
SCHEMBL8652680 0.89 NR3C1 (0.34) NR3C1RORCCCL5CCR5SLC40A1
SCHEMBL8764537 0.87
SCHEMBL8763949 0.87 NR3C1 (0.34) NR3C1RORCCCL5CCR5SLC40A1
SCHEMBL8762814 0.86 NR3C1 (0.34) NR3C1RORCSLC40A1
SCHEMBL8764193 0.86 SLC40A1 (0.31) RORCSLC40A1ESR1
SCHEMBL8764008 0.83 CTSS (0.31)
SCHEMBL8764078 0.83 RORC (0.32) NR3C1RORCCCL5CCR5
SCHEMBL8731899 0.83 SLC40A1 (0.32) NR3C1SLC40A1ESR1
SCHEMBL8762722 0.83 NR3C1 (0.32) NR3C1CCL5CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed