Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765289 | 0.88 | ALDH1A1 (0.43) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL8764624 | 0.88 | ALDH1A1 (0.43) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL10943765 | 0.88 | ALDH1A1 (0.48) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL3947688 | 0.82 | SKP2 (0.53) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL307367 | 0.75 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ESR1ESR2POLB | |
| SCHEMBL3419810 | 0.75 | ALDH1A1 (0.54) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL10876001 | 0.74 | LOXL2 (0.39) | ALDH1A1GAACYP3A4RAB9AMEN1 | |
| SCHEMBL11896057 | 0.74 | SLC6A2 (0.40) | ALDH1A1GAARAB9AMAPTMEN1 | |
| SCHEMBL237201 | 0.73 | SKP2 (0.61) | ALDH1A1GAACYP3A4RAB9AKDM4E | |
| SCHEMBL8763541 | 0.73 | ALDH1A1 (0.31) | ALDH1A1GAACYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |