Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911627 | 0.84 | KDM4E (0.52) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL29755650 | 0.84 | KDM4E (0.52) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3658983 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3015617 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL49257 | 0.79 | CYP1A2 (0.60) | HPGDL3MBTL1MAPTNPSR1LMNA | |
| SCHEMBL8765729 | 0.79 | KDM4E (0.54) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7055886 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL15380425 | 0.78 | KDM4E (0.50) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL843196 | 0.78 | MAPT (0.56) | ALDH1A1L3MBTL1MAPTNPSR1LMNA | |
| SCHEMBL29982369 | 0.77 | HTR7 (0.58) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |