Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843196 | 0.82 | MAPT (0.56) | L3MBTL1TP53MAPK1CYP1A2CYP2C9 | |
| SCHEMBL3658983 | 0.81 | ALDH1A1 (0.42) | KDM4EHTR1BL3MBTL1RAB9ATDP1 | |
| SCHEMBL8764972 | 0.80 | KDM4E (0.43) | KDM4EHTR1BL3MBTL1TP53MAPK1 | |
| SCHEMBL991008 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2679382 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL991234 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2679806 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2679170 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL991604 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL57744 | 0.80 | LMNA (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |