Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212289 | 0.85 | TRPA1 (0.47) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL5315230 | 0.83 | LMNA (0.39) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL16519866 | 0.81 | TRPA1 (0.60) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL8871076 | 0.80 | SLC6A2 (0.32) | TRPA1 | |
| Ammonia Solution, Strong SCHEMBL28227842 | 0.77 | TRPA1 (0.42) | TRPA1TSHRHSD17B10ALDH1A1POLB | |
| SCHEMBL13806578 | 0.76 | TRPA1 (0.65) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL8765423 | 0.73 | TRPA1 (0.50) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL287059 | 0.73 | PTGS1 (0.38) | ALDH1A1TDP1KMT2A | |
| SCHEMBL14861240 | 0.73 | TRPA1 (0.54) | TRPA1LMNATSHRHSD17B10ALDH1A1 | |
| SCHEMBL10357490 | 0.72 | LMNA (0.37) | TRPA1LMNATSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |
| EP-0505972-B1 | Process for producing styrenic copolymer | IDEMITSU KOSAN CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0505972-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |