Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765443 | 0.80 | TRPA1 (0.48) | TRPA1 | |
| SCHEMBL2573918 | 0.72 | ALDH1A1 (0.43) | TRPA1 | |
| SCHEMBL19354128 | 0.71 | KDM4E (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL28227842 | 0.70 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL8766176 | 0.69 | SLC6A2 (0.43) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL14670296 | 0.69 | TSHR (0.43) | SLC6A3 | |
| SCHEMBL5315230 | 0.68 | LMNA (0.39) | TRPA1 | |
| SCHEMBL287059 | 0.67 | PTGS1 (0.38) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL4854314 | 0.66 | SLC6A2 (0.37) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL276579 | 0.66 | BCL2L1 (0.39) | SLC6A2HTR2ASLC6A4HRH1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681563-A | THERAPY FOR PENICILLIN RESISTANT INFECTIONS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5597817-A | INHIBITORS OF LACTAMASES, TREATMENT OF PENCILLIN RESISTANCE INFECTIONS | SOUTHERN METHODIST UNIVERSITY (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996017848-A1 | 7-VINYLIDENE CEPHALOSPORINS AND METHODS OF USING THE SAME | SOUTHERN METHODIST UNIVERSITY (US) | 1996-06-13 | — | — | WO | disclosed |