SCHEMBL8765447

SCHEMBL8765447

Fc1cccc(N(c2cccc(F)c2)c2cccc(N(c3cccc(F)c3)c3cccc(F)c3)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
NFE2L2 Q16236 3/20 0.42
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
PKM P14618 1/20 0.38
MAPK1 P28482 1/20 0.38
THPO P40225 1/20 0.38
CHRM5 P08912 1/20 0.38
GRM5 P41594 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
TAAR1 Q96RJ0 4/20 0.38
PARP1 P09874 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26849291 0.92 ACHE (0.42) ACHENFE2L2CES2CES1NPC1
SCHEMBL21173399 0.90 NFE2L2 (0.45) ACHENFE2L2CES2CES1KMT2A
SCHEMBL12774513 0.90 NFE2L2 (0.45) ACHENFE2L2CES2CES1KMT2A
SCHEMBL14186204 0.88 L3MBTL1 (0.48) ACHENFE2L2CES2CES1NPC1
SCHEMBL13608532 0.85 ABCG2 (0.40) ACHENFE2L2KMT2ACYP1A2CYP3A4
SCHEMBL21173400 0.84 ACHE (0.64) ACHENFE2L2NPC1RAB9AKMT2A
SCHEMBL23347209 0.83 ALDH1A1 (0.43) NFE2L2KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL23844919 0.83 ALDH1A1 (0.43) NFE2L2KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL20671378 0.83 ACHE (0.50) ACHENFE2L2NPC1RAB9AKMT2A
SCHEMBL12922773 0.83 CETP (0.44) NFE2L2NPC1RAB9AKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420207-B1 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO LTD (JP) 1997-08-13 EP disclosed
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
US-5185228-A Binder resin, charge transfer material; stability MITA INDUSTRIAL CO., LTD. (JP) 1993-02-09 US disclosed
US-5128229-A Polycarbonate, m-phenylenediamine derivative MITA INDUSTRIAL CO., LTD. (JP) 1992-07-07 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0420207-A2 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO. LTD. (JP) 1991-04-03 EP disclosed
EP-0413338-A1 Electrophotosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1991-02-20 EP disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed