SCHEMBL8765696

SCHEMBL8765696

[O]c1ccc(C(Cl)(Cl)Cl)cn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720313 0.78 TSHR (0.36) TSHRKMT2A
SCHEMBL1450952 0.76 KMT2A (0.52) TSHRKMT2A
SCHEMBL31500776 0.73 TSHR (0.41) TSHR
SCHEMBL4985623 0.73 TSHR (0.41) TSHR
SCHEMBL8778864 0.71 TSHR (0.35) TSHR
SCHEMBL9253335 0.71 ADRA2A (0.36) TSHRKMT2A
SCHEMBL8778877 0.71 CYP2A6 (0.35) TSHRKMT2A
SCHEMBL8765704 0.71 TSHR (0.35) TSHRKMT2A
SCHEMBL11821273 0.69 MAPT (0.44)
SCHEMBL8004704 0.68 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed