Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765696 | 0.76 | TSHR (0.35) | KMT2ATSHR | |
| SCHEMBL15226708 | 0.76 | KMT2A (0.47) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL811160 | 0.75 | NPSR1 (0.53) | KMT2ARAB9APTGS1NPC1SMN1; SMN2 | |
| SCHEMBL29595709 | 0.75 | NPSR1 (0.53) | KMT2ARAB9APTGS1NPC1SMN1; SMN2 | |
| SCHEMBL29427147 | 0.73 | KMT2A (0.48) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL8522 | 0.73 | KMT2A (0.48) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL4149032 | 0.73 | TRPV4 (0.60) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL20526137 | 0.73 | KMT2A (0.48) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL12402864 | 0.71 | KMT2A (0.47) | KMT2ARAB9APTGS1NPC1MAPT | |
| SCHEMBL764716 | 0.71 | KMT2A (0.47) | KMT2ARAB9APTGS1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3348547-B1 | BENZIMIDAZOLE DERIVATIVES AS NAV 1.7 (SODIUM CHANNEL, VOLTAGE-GATED, TYPE IX, ALPHA SUBUNIT (SCN9A)) INHIBITORS FOR TREATING PAIN, DYSURIA AND MULTIPLE SCLEROSIS | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2020-07-22 | — | — | EP | claimed |
| US-8383839-B2 | Heterocyclidene acetamide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-02-26 | — | — | US | claimed |
| US-20110112071-A1 | NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-05-12 | — | — | US | claimed |
| US-7910751-B2 | Heterocyclidene acetamide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-22 | — | — | US | claimed |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-11-10 | — | — | US | claimed |
| EP-1538138-A1 | SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2005-06-08 | — | — | EP | claimed |
| US-20040248877-A1 | Polycyclic diazodioxide-based Bcl-2 protein antagonists and use thereof | RICERCA BIOSCIENCES, LLC. | 2004-12-09 | — | — | US | claimed |
| WO-2004099162-A1 | POLYCYCLIC DIAZODIOXIDE-BASED BCL-2 PROTEIN ANTAGONIST | RICERCA BIOSCIENCES, LLC. (US) | 2004-11-18 | — | — | WO | claimed |
| US-20030125329-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-07-03 | — | — | US | claimed |
| US-20030125328-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-07-03 | — | — | US | claimed |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| EP-0896532-B1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2002-10-02 | — | — | EP | claimed |
| EP-1115693-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| EP-0896532-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | Novartis AG (CH) | 1999-02-17 | — | — | EP | claimed |
| US-5837734-A | Method for the treatment of coccidioidomycosis in warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-11-17 | — | — | US | claimed |
| WO-1997040826-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | claimed |
| US-5416102-A | Administering orally, by injection or implantation, a dosage of flea growth inhibiting benzoyl urea compound | CIBA-GEIGY CORPORATION (US) | 1995-05-16 | — | — | US | claimed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| EP-0049111-A1 | Phenoxybutyltriazole compound, agricultural and horticultural fungicidal composition containing the same, and process for producing the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1982-04-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125328-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KMT2A 2608/4885RAB9A 3063/4885PTGS1 2773/4885 |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | KMT2A 3855/4885RAB9A 3601/4885PTGS1 2037/4885 |
| US-20030125329-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KMT2A 2608/4885RAB9A 3063/4885PTGS1 2773/4885 |
| US-20040248877-A1 | Polycyclic diazodioxide-based Bcl-2 protein antagonists and use thereof | BCL2L2, BCL2, BCL2L1 | KMT2A 2719/4885RAB9A 1029/4885PTGS1 2012/4885 |
| US-20050250822-A1 | Substituted benzanilide compound and noxious organism controlling agent | GCN1, L3MBTL3, L3MBTL4 | KMT2A 2360/4885RAB9A 456/4885PTGS1 2375/4885 |
| US-20110112071-A1 | NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE | TRPV1, TRPV3, TRPA1 | KMT2A 3094/4885RAB9A 2499/4885PTGS1 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.