Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765729 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL55705 | 0.78 | ALDH1A1 (0.37) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL482954 | 0.78 | ALDH1A1 (0.58) | KDM4EALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL7049447 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL7904254 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6003548 | 0.76 | DRD1 (0.46) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL3015617 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL7055886 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL11195993 | 0.74 | CA12 (0.36) | KDM4EALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL28033604 | 0.73 | ALDH1A1 (0.64) | KDM4EALDH1A1AGXTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |