Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.85 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.85 |
| ▸ | CA1 | P00915 | 7/20 | 0.64 |
| ▸ | CA2 | P00918 | 7/20 | 0.64 |
| ▸ | ACHE | P22303 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765743 | 1.00 | MTNR1A (0.85) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3854031 | 0.92 | MTNR1A (1.00) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3975748 | 0.86 | MTNR1A (0.90) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8766426 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8766632 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8765257 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8766448 | 0.80 | MTNR1A (0.73) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8766720 | 0.77 | MTNR1B (0.55) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8766729 | 0.77 | MTNR1B (0.55) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL14277944 | 0.77 | TAS1R3 (0.64) | MTNR1AMTNR1BCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |