Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766729 | 1.00 | MTNR1B (0.55) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL629488 | 0.92 | MTNR1A (0.61) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL8766020 | 0.80 | DRD2 (0.51) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL8765749 | 0.77 | MTNR1A (0.85) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL8765743 | 0.77 | MTNR1A (0.85) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL4000915 | 0.77 | DRD2 (0.58) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL8765765 | 0.77 | DRD2 (0.58) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL4000913 | 0.77 | DRD2 (0.58) | MTNR1BMTNR1ADRD2DRD3CA1 | |
| SCHEMBL3817898 | 0.77 | ESR1 (0.49) | MTNR1BMTNR1ADRD2GABRA1GABRB2 | |
| SCHEMBL3823105 | 0.77 | ESR1 (0.49) | MTNR1BMTNR1ADRD2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |