Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767006 | 0.88 | PTPN1 (0.60) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL22198612 | 0.78 | BACE1 (0.47) | PTPN1MME | |
| SCHEMBL20375820 | 0.77 | CASP3 (0.44) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL9444219 | 0.74 | OPRM1 (0.47) | CTSLCTSBCTSSOPRM1 | |
| SCHEMBL30004432 | 0.74 | FCER2 (0.53) | PTPN1MMECTSLFCER2MMP1 | |
| SCHEMBL13402940 | 0.74 | MMP1 (0.54) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL13402948 | 0.74 | MMP1 (0.51) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL30999528 | 0.73 | ACE (0.59) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL13783684 | 0.73 | FCER2 (0.48) | PTPN1PTPN2PTPRAPTPN6PTPN11 | |
| SCHEMBL16326771 | 0.73 | FCER2 (0.48) | PTPN1PTPN2PTPRAPTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777681-A2 | CYCLIC CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1997-06-11 | — | — | EP | claimed |
| WO-1996006108-A2 | CYCLIC CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-02-29 | — | — | WO | claimed |