Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838754 | 0.83 | ALDH1A1 (0.42) | PDE7ASLC6A4SLC6A3 | |
| SCHEMBL1255414 | 0.82 | ESR1 (0.61) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL1257322 | 0.82 | ESR1 (0.61) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL18037034 | 0.79 | HDAC4 (0.42) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL11840369 | 0.78 | OPRM1 (0.54) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL17982792 | 0.78 | HDAC4 (0.47) | HDAC4 | |
| SCHEMBL1256628 | 0.78 | ESR1 (0.47) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL9729622 | 0.77 | MEN1 (0.53) | HSD11B1HSD11B2HDAC4PSEN1PSEN2 | |
| SCHEMBL5894861 | 0.76 | PGR (0.46) | — | |
| SCHEMBL29919493 | 0.76 | PGR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |