Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243405 | 0.79 | LMNA (0.47) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL18949976 | 0.77 | HTR2A (0.42) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL7560523 | 0.77 | UGT2B7 (0.47) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL240650 | 0.77 | UGT2B7 (0.47) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL241213 | 0.76 | MEN1 (0.40) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL13217608 | 0.76 | HTR2A (0.41) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL22288182 | 0.75 | TACR3 (0.41) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL27654127 | 0.74 | ALDH1A1 (0.43) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL27654129 | 0.74 | ALDH1A1 (0.43) | HTR2AL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL2113581 | 0.74 | MAPT (0.41) | L3MBTL1CYP1A2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787116-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | Akzo Nobel N.V. (NL) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011894-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | AKZO NOBEL N.V. (NL) | 1996-04-25 | — | — | WO | disclosed |